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Stem Cell Therapy involves the use of stem cells to treat different diseases. These are non-differentiated cells of a multicellular organism. All the cells in the body are specialized for a specific function but they are the only cells without an assigned function. They can differentiate into any type of cell as and when required by the body and can proliferate rapidly to produce multiple copies of a specific type. Sources of stem cells are embryos and adult body tissues. In the adults, stem cells are present in bone marrow, brain, liver, skin, skeletal muscles, blood and blood vessels. While embryonic stem cells are derived from a blastocyst. Nowadays, Umbilical cord is being stored under suitable conditions to get stem cells from it if needed. This is useful as chances of transplant rejection are less because stem cells are derived from your own umbilical cord.
Bone Marrow Transplant is the most commonly used method to treat various types of cancers such as lymphoma, multiple myeloma, and leukemia, etc. through stem cells. It is also used to treat brain diseases, cardiovascular diseases and cell deficiencies such as diabetes mellitus. Recently, anti-aging stem cell treatments have gain fame. It is used to restore your youth and beauty.
The procedure of stem cell therapy starts with removing stem cells from your body or from the donor’s body. The cells are collected from different body parts depending upon the need. After collection, the cells are processed according to the purpose for which they are extracted. The processed stem cells are injected into the specific area of your body using ultrasound or X-ray guidance. Anesthetics are used and the procedure is done under sterile conditions. It is necessary to make sure that the cells are reaching the desired area so that the improvement is better and quicker. There are three types of stem cell transplant:
Each type of stem cell transplant involves different methods, procedures, and techniques with different side effects and risks. The one suitable for you depends upon your age, health, and physical conditions.
The length of stay in the hospital varies in accordance with the condition for which stem cell therapy is being done. It is usually a 3 to 4 hours procedure (in-patient) in which stem cells are introduced into the body using syringes or catheter. Different factors are considered to decide the length of your stay in the hospital. These factors are:
Your stay in the hospital is longer for an allogeneic transplant as compared to an autologous transplant and you're free to leave Brazil the very next day, although it's advised to stay at least a few days in case you have further questions for the medical staff. But of course, these can be asked over the phone/email or directed towards your local medical team back home.
Complete recovery time varies from 2 to 12 weeks when the patient begins to feel pain relief. However, you can return to your routine work a couple of days after going through the transplant. Recovery depends upon your physical condition before and after the transplant. Over a period of 6 to 12 months, further improvements are seen in the patients. During the process, antibiotics and other drugs are prescribed. These drugs prevent transplant rejection and graft-host diseases. Allogenic stem cell transplant takes longer to recover than an autologous transplant.
It is advised to keep in contact with your doctor and to visit him/her on a regular basis. Apart from this, the following points should be considered:
There is a significant success rate seen in patients having gone through the transplant, however, it is not always successful due to various reasons, one being the transplant rejection. This is common in the allogeneic type of stem cell transplant.
Exosomes are being used as an alternative to stem cell therapy. They are lipid bilayer surrounded vesicles secreted by live cells. They contain mRNA, proteins, chaperons, and various signaling molecules. They work as a natural carrier system for the transport of these substances. They function as a messenger within the body carrying information from one cell to the other. Stem cell therapy can be enhanced using exosomes. They help the body’s natural healing ability to increase the pace of recovery. Sometimes, stem cell therapy and exosomes are given together for better results.
Stem cell therapy is mostly being used for the treatment of cancer patients. Before the therapy, cancer cells are present within the body. After going through the therapy, stem cells replace cancer cells with healthy cells. This treats cancer, giving the patient a healthy life.
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Brazil is South America’s largest country and has a population of over 209 million people and is famous for its football (soccer) and carnival traditions. Steeped in natural beauty, with the Iguacu Falls and Amazon Rainforest and famed for its 98-foot tall statue of Christ the Redeemer. Brazil offers more than 60 JCI-accredited facilities and is one of the leading destinations in the world for cosmetic surgery, with Stem Cell Therapy procedures being especially popular. Doctors are often Western-trained and speak English on top of Portuguese and Spanish. Local accreditations include the Consortium of Brazilian Accreditation and the Brazilian Hospital Medical Quality Organization (ONA). Popular locations within Brazil include the capital Brasilia, Rio de Janeiro, Sao Paulo, and Curitiba.
As a large country, the weather in Brazil varies from tropical in the north to temperate in the south. A large part of the country lies in the topics. Brazil is a year-round destination because it has a steady average annual temperature. The temperature rarely drops below 20 °C.
Winter in Brazil starts in May and ends in September. The weather remains tropical in the north with an average temperature ranging between 20 °C to 30 °C. In Rio de Janeiro, the temperature varies between 14 °C to 25 °C. However, the evenings usually feel a lot colder. There are a lot of rainy days in Rio during this season. The weather in São Paulo is colder than Rio.
The temperature in Rio rise between November and March, with the highest temperature of around 40 °C but with a thermal sensation of around 50 °C. The Rain rarely lasts long during these months. In the north of Brazil, the rainy season starts in December. March and May see the heaviest rainfall. It’s hot and humid with frequent rain throughout the year in the Amazon.
The most popular international airports are Rio de Janeiro–Antonio Carlos Jobim International Airport (popularly known as Galeão International Airport) and São Paulo/Guarulhos–Governador André Franco Montoro International Airport. Both airports serve domestic and international flights to many cities around the globe. The airports mainly serve major airlines but there are budget airlines such as Norwegian Air UK. Tourists can take taxis, bus, train, or car rental from both airports to the city centers.
Brazil is really big, so there will be a lot of long-distance travel to get around the country. The easiest and fastest way to get from one city to another is by domestic flights. The only downside is that the tickets are very expensive. LATAM and GOL airline offer multi-trip tickets or air pass. The most economical option is to buy an air pass if you plan to visit a number of different cities.
Buses are popular in Brazil, servicing most areas of the country. The bus system is excellent and provides a comfortable and economical way of travel. Be aware that the distance can be really tiring and overwhelming; some trips can take over 40 hours. The buses are operated by hundreds of different private companies, but the price is standardized. The fare varies from 75 BRL to 240 BRL. There are luxurious buses too.
A good way to get around major cities like São Paulo and Rio is to use Brazil Metro (subway). The fares are around 3.50 BRL to 3.80 BRL. You can purchase rechargeable travel cards. The metro does not operate at night. Be sure to watch your belongings at all times when traveling on the metro.
Taxis run on a metered system, but if you travel a bit further out of town, you need to negotiate the price with the driver. It is best to phone for a taxi or pick one up at a taxi station and make sure to get into a licensed taxi. Ferries and other water travel are important in many parts of Brazil.
Citizens of 72 countries and regions can enter and stay in Brazil for up to 90 days. An identity document is accepted instead of a passport in some cases. Other nationalities (including China and India) need to apply and obtain a visa before entering the country. It is advisable to check to the nearest Embassy of Brazil for more information regarding visa.
e-Visa is available and valid for two years for stays up to 90 days per year.
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